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Genetically regulated gene expression and proteins revealed discordant effects

BACKGROUND: Although gene-expression (GE) and protein levels are typically strongly genetically regulated, their correlation is known to be low. Here we investigate this phenomenon by focusing on the genetic background of this correlation in order to understand the similarities and differences in th...

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Detalles Bibliográficos
Autores principales: Pott, Janne, Garcia, Tarcyane, Hauck, Stefanie M., Petrera, Agnese, Wirkner, Kerstin, Loeffler, Markus, Kirsten, Holger, Peters, Annette, Scholz, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126407/
https://www.ncbi.nlm.nih.gov/pubmed/35604899
http://dx.doi.org/10.1371/journal.pone.0268815