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Functional Phenotypes of Peritoneal Macrophages Upon AMD3100 Treatment During Colitis-Associated Tumorigenesis

CXCL12 and its receptor CXCR4 are independent prognostic factors in colorectal cancer. AMD3100 is the most frequently used FDA-approved antagonist that targets the CXCL12-CXCR4 axis in clinical trials. We aimed to explore the role of AMD3100 and its effect on peritoneal macrophages' functional...

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Detalles Bibliográficos
Autores principales: Wu, Shuai, Luo, Weiwei, Wu, Xing, Shen, Zhaohua, Wang, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126482/
https://www.ncbi.nlm.nih.gov/pubmed/35615089
http://dx.doi.org/10.3389/fmed.2022.840704