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Alcohol consumption, polygenic risk score, and early- and late-onset colorectal cancer risk
BACKGROUND: Evidence is lacking on the impact of alcohol consumption on colorectal cancer (CRC) risk (overall and by age at diagnosis) by polygenic risk score (PRS) levels, and it is unclear how the magnitude of CRC risk associated with alcohol consumption compares to the magnitude of genetically de...
Autores principales: | Chen, Xuechen, Li, Hengjing, Guo, Feng, Hoffmeister, Michael, Brenner, Hermann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126769/ https://www.ncbi.nlm.nih.gov/pubmed/35747198 http://dx.doi.org/10.1016/j.eclinm.2022.101460 |
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