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A meiotic switch in lysosome activity supports spermatocyte development in young flies but collapses with age

Gamete development ultimately influences animal fertility. Identifying mechanisms that direct gametogenesis, and how they deteriorate with age, may inform ways to combat infertility. Recently, we found that lysosomes acidify during oocyte maturation in Caenorhabditis elegans, suggesting that a meiot...

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Detalles Bibliográficos
Autores principales: Butsch, Tyler J., Dubuisson, Olga, Johnson, Alyssa E., Bohnert, K. Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126793/
https://www.ncbi.nlm.nih.gov/pubmed/35620438
http://dx.doi.org/10.1016/j.isci.2022.104382