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A meiotic switch in lysosome activity supports spermatocyte development in young flies but collapses with age
Gamete development ultimately influences animal fertility. Identifying mechanisms that direct gametogenesis, and how they deteriorate with age, may inform ways to combat infertility. Recently, we found that lysosomes acidify during oocyte maturation in Caenorhabditis elegans, suggesting that a meiot...
Autores principales: | Butsch, Tyler J., Dubuisson, Olga, Johnson, Alyssa E., Bohnert, K. Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126793/ https://www.ncbi.nlm.nih.gov/pubmed/35620438 http://dx.doi.org/10.1016/j.isci.2022.104382 |
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