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Pyroglutamate Aβ cascade as drug target in Alzheimer’s disease
One of the central aims in Alzheimer’s disease (AD) research is the identification of clinically relevant drug targets. A plethora of potential molecular targets work very well in preclinical model systems both in vitro and in vivo in AD mouse models. However, the lack of translation into clinical s...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126800/ https://www.ncbi.nlm.nih.gov/pubmed/34880449 http://dx.doi.org/10.1038/s41380-021-01409-2 |