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Developmental oxidative stress leads to T-type Ca(2+) channel hypofunction in thalamic reticular nucleus of mouse models pertinent to schizophrenia

Impairment of parvalbumin interneurons induced by oxidative stress (OxS) is a “hub” on which converge several genetic and environmental risk factors associated with schizophrenia. In patients, this could be a mechanism leading to anomalies of the thalamic reticular nucleus (TRN) whose major neuronal...

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Detalles Bibliográficos
Autores principales: El Khoueiry, Corinne, Cabungcal, Jan-Harry, Rovó, Zita, Fournier, Margot, Do, Kim Q., Steullet, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126813/
https://www.ncbi.nlm.nih.gov/pubmed/35079122
http://dx.doi.org/10.1038/s41380-021-01425-2