Insulin-like growth factor I mitigates post-traumatic stress by inhibiting AMP-kinase in orexin neurons

Maladaptive coping behaviors are probably involved in post-traumatic stress disorders (PTSD), but underlying mechanisms are incompletely understood. We now report that mice lacking functional insulin-like growth factor I (IGF-I) receptors in orexin neurons of the lateral hypothalamus (Firoc mice) ar...

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Detalles Bibliográficos
Autores principales: Fernández de Sevilla, M. Estrella, Pignatelli, Jaime, Zegarra-Valdivia, Jonathan A., Mendez, Pablo, Nuñez, Angel, Torres Alemán, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126821/
https://www.ncbi.nlm.nih.gov/pubmed/35115701
http://dx.doi.org/10.1038/s41380-022-01442-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126821/
https://www.ncbi.nlm.nih.gov/pubmed/35115701
http://dx.doi.org/10.1038/s41380-022-01442-9

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