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NANOG confers resistance to complement-dependent cytotoxicity in immune-edited tumor cells through up-regulating CD59

Cancer immunoediting drives the adaptation of tumor cells to host immune surveillance. Previously, we have demonstrated that immunoediting driven by cytotoxic T lymphocytes (CTLs) enriches NANOG(+) tumor cells with immune-refractory properties. Here, we found that CTL-mediated immune pressure trigge...

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Detalles Bibliográficos
Autores principales: Son, Sung Wook, Cho, Eunho, Cho, Hanbyoul, Woo, Seon Rang, Lee, Hyo-Jung, Oh, Se Jin, Kim, Suyeon, Kim, Jae-Hoon, Chung, Eun Joo, Chung, Joon-Yong, Kim, Min Gyu, Song, Kwon-Ho, Kim, Tae Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126891/
https://www.ncbi.nlm.nih.gov/pubmed/35606403
http://dx.doi.org/10.1038/s41598-022-12692-6