Mitochondrial thioredoxin system is required for enhanced stress resistance and extended longevity in long-lived mitochondrial mutants

Mild impairment of mitochondrial function has been shown to increase lifespan in genetic model organisms including worms, flies and mice. To better understand the mechanisms involved, we analyzed RNA sequencing data and found that genes involved in the mitochondrial thioredoxin system, trx-2 and trx...

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Detalles Bibliográficos
Autores principales: Harris-Gauthier, Namastheé, Traa, Annika, AlOkda, Abdelrahman, Moldakozhayev, Alibek, Anglas, Ulrich, Soo, Sonja K., Van Raamsdonk, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126954/
https://www.ncbi.nlm.nih.gov/pubmed/35598379
http://dx.doi.org/10.1016/j.redox.2022.102335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126954/
https://www.ncbi.nlm.nih.gov/pubmed/35598379
http://dx.doi.org/10.1016/j.redox.2022.102335

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