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Involvement of the SIRT1/PGC-1α Signaling Pathway in Noise-Induced Hidden Hearing Loss

Objective: To establish an animal model of noise-induced hidden hearing loss (NIHHL), evaluate the dynamic changes in cochlear ribbon synapses and cochlear hair cell morphology, and observe the involvement of the SIRT1/PGC-1α signaling pathway in NIHHL. Methods: Male guinea pigs were randomly divide...

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Detalles Bibliográficos
Autores principales: Liu, Yu-Hui, Jiang, Yi-Hong, Li, Cong-Cong, Chen, Xue-Min, Huang, Li-Gui, Zhang, Min, Ruan, Bai, Wang, Xiao-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127058/
https://www.ncbi.nlm.nih.gov/pubmed/35620603
http://dx.doi.org/10.3389/fphys.2022.798395