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Pharmacokinetic Characteristics of Siponimod in Healthy Volunteers and Patients With Multiple Sclerosis: Analyses of Published Clinical Trials

Objectives: This study aimed to investigate the pharmacokinetic characteristics of siponimod in healthy volunteers and patients with MS based on aggregated data from published clinical trials, and to explore the factors influencing siponimod exposure. Methods: A total of 476 siponimod plasma concent...

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Detalles Bibliográficos
Autores principales: Chaoyang, Chen, Xiu, Dong, Ran, Wei, Lingyun, Ma, Simiao, Zhao, Ruoming, Li, Enyao, Zhang, Ying, Zhou, Yimin, Cui, Zhenming, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127076/
https://www.ncbi.nlm.nih.gov/pubmed/35620290
http://dx.doi.org/10.3389/fphar.2022.824232