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Renal peritumoral adipose tissue undergoes a browning process and stimulates the expression of epithelial-mesenchymal transition markers in human renal cells

Tumor cells can interact with neighboring adipose cells and adipocyte dedifferentiation appears to be an important aspect of tumorigenesis. We evaluated the size of adipocytes in human adipose explants from normal (hRAN) and kidney cancer (hRAT); changes in the expression of WAT and BAT/beige marker...

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Detalles Bibliográficos
Autores principales: Ferrando, Matías, Bruna, Flavia Alejandra, Romeo, Leonardo Rafael, Contador, David, Moya-Morales, Daiana Lorena, Santiano, Flavia, Zyla, Leila, Gomez, Silvina, Lopez-Fontana, Constanza Matilde, Calvo, Juan Carlos, Carón, Rubén Walter, Toneatto, Judith, Pistone-Creydt, Virginia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127098/
https://www.ncbi.nlm.nih.gov/pubmed/35606546
http://dx.doi.org/10.1038/s41598-022-12746-9