Opening opportunities for K(d) determination and screening of MHC peptide complexes

An essential element of adaptive immunity is selective binding of peptide antigens by major histocompatibility complex (MHC) class I proteins and their presentation to cytotoxic T lymphocytes. Using native mass spectrometry, we analyze the binding of peptides to an empty disulfide-stabilized HLA-A*0...

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Detalles Bibliográficos
Autores principales: Kopicki, Janine-Denise, Saikia, Ankur, Niebling, Stephan, Günther, Christian, Anjanappa, Raghavendra, Garcia-Alai, Maria, Springer, Sebastian, Uetrecht, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127112/
https://www.ncbi.nlm.nih.gov/pubmed/35606511
http://dx.doi.org/10.1038/s42003-022-03366-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127112/
https://www.ncbi.nlm.nih.gov/pubmed/35606511
http://dx.doi.org/10.1038/s42003-022-03366-0

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