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Towards discovery of inhibitors of the undecaprenyl-pyrophosphate phosphatase BacA by virtual high-throughput screening

Increasing resistance to common antibiotics is becoming a major challenge that requires the development of new antibacterial agents. Peptidoglycan is an essential heteropolymer of the bacterial envelope that ensures the integrity and shape of all bacteria and is also an important target for antibiot...

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Detalles Bibliográficos
Autores principales: Jukič, Marko, Auger, Rodolphe, Folcher, Victor, Proj, Matic, Barreteau, Hélène, Gobec, Stanislav, Touzé, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127117/
https://www.ncbi.nlm.nih.gov/pubmed/35664230
http://dx.doi.org/10.1016/j.csbj.2022.05.010