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Towards discovery of inhibitors of the undecaprenyl-pyrophosphate phosphatase BacA by virtual high-throughput screening
Increasing resistance to common antibiotics is becoming a major challenge that requires the development of new antibacterial agents. Peptidoglycan is an essential heteropolymer of the bacterial envelope that ensures the integrity and shape of all bacteria and is also an important target for antibiot...
Autores principales: | Jukič, Marko, Auger, Rodolphe, Folcher, Victor, Proj, Matic, Barreteau, Hélène, Gobec, Stanislav, Touzé, Thierry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127117/ https://www.ncbi.nlm.nih.gov/pubmed/35664230 http://dx.doi.org/10.1016/j.csbj.2022.05.010 |
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