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Sex specific effects of buprenorphine on behavior, astrocytic opioid receptor expression and neuroinflammation after pediatric traumatic brain injury in mice

Children who suffered traumatic brain injury (TBI) often experience acute and chronic pain, which is linked to a poor quality of life. Buprenorphine (BPN) is commonly used to treat moderate to severe persistent pain in children, however, the efficacy and safety profile of BPN in the pediatric popula...

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Detalles Bibliográficos
Autores principales: Hamood, Yesmine, Abdullah, Mauda, El Ghoul, Hassan, Saad, Nazeh, Dysko, Robert C., Zhang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127176/
https://www.ncbi.nlm.nih.gov/pubmed/35620644
http://dx.doi.org/10.1016/j.bbih.2022.100469