Cargando…
Protocol for drug screening of patient-derived tumor organoids using high-content fluorescent imaging
High-content imaging of tumor organoids (TOs) treated with therapeutic agents provides detailed cell viability readouts at the organoid level. In contrast, most used protocols provide one number per well. While requiring the use of inverted microscopy with an automated stage, this protocol can provi...
Autores principales: | Larsen, Brian M., Cancino, Andrea, Shaxted, Jenna M., Salahudeen, Ameen A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127194/ https://www.ncbi.nlm.nih.gov/pubmed/35620075 http://dx.doi.org/10.1016/j.xpro.2022.101407 |
Ejemplares similares
-
High-throughput drug screening of fine-needle aspiration-derived cancer organoids
por: Bergdorf, Kensey, et al.
Publicado: (2020) -
Normal and tumor-derived organoids as a drug screening platform for tumor-specific drug vulnerabilities
por: Calandrini, Camilla, et al.
Publicado: (2022) -
Generation of glioblastoma patient-derived organoids and mouse brain orthotopic xenografts for drug screening
por: Gamboa, Christian Moya, et al.
Publicado: (2021) -
Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors
por: Oudin, Anaïs, et al.
Publicado: (2021) -
Patient-Derived Tumor Organoid Rings for Histologic Characterization and High-Throughput Screening
por: Nguyen, Huyen Thi Lam, et al.
Publicado: (2020)