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MicroRNA-200c coordinates HNF1 homeobox B and apolipoprotein O functions to modulate lipid homeostasis in alcoholic fatty liver disease

Hepatic steatosis is an initial manifestation of alcoholic liver disease. An imbalance of hepatic lipid processes including fatty acid uptake, esterification, oxidation, and triglyceride secretion leads to alcoholic fatty liver (AFL). However, the precise molecular mechanisms underlying the pathogen...

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Detalles Bibliográficos
Autores principales: Mostofa, Md Golam, Tran, Melanie, Gilling, Shaynian, Lee, Grace, Fraher, Ondine, Jin, Lei, Kang, Hyunju, Park, Young-Ki, Lee, Ji-Young, Wang, Li, Shin, Dong-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127369/
https://www.ncbi.nlm.nih.gov/pubmed/35460694
http://dx.doi.org/10.1016/j.jbc.2022.101966