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Sequencing of Cutaneous Squamous Cell Carcinoma Primary Tumors and Patient-Matched Metastases Reveals ALK as a Potential Driver in Metastases and Low Mutational Concordance in Immunocompromised Patients

Cutaneous squamous cell carcinoma is a common skin cancer that is responsible for 1,000,000 cases and up to 9,000 deaths annually in the United States. Metastases occur in 2–5% of patients and are responsible for significant morbidity and mortality. The objective of this study is to perform targeted...

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Detalles Bibliográficos
Autores principales: Lobl, Marissa B., Clarey, Dillon D., Higgins, Shauna, Sutton, Adam, Wysong, Ashley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127419/
https://www.ncbi.nlm.nih.gov/pubmed/35620707
http://dx.doi.org/10.1016/j.xjidi.2022.100122