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Drug Repositioning with GraphSAGE and Clustering Constraints Based on Drug and Disease Networks

The understanding of therapeutic properties is important in drug repositioning and drug discovery. However, chemical or clinical trials are expensive and inefficient to characterize the therapeutic properties of drugs. Recently, artificial intelligence (AI)-assisted algorithms have received extensiv...

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Detalles Bibliográficos
Autores principales: Zhang, Yuchen, Lei, Xiujuan, Pan, Yi, Wu, Fang-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127467/
https://www.ncbi.nlm.nih.gov/pubmed/35620297
http://dx.doi.org/10.3389/fphar.2022.872785