The metalloprotease ADAM10 generates soluble interleukin-2 receptor alpha (sCD25) in vivo

The cytokine interleukin-2 (IL-2) plays a critical role in controlling the immune homeostasis by regulating the proliferation and differentiation of immune cells, especially T cells. IL-2 signaling is mediated via the IL-2 receptor (IL-2R) complex, which consists of the IL-2Rα (CD25), the IL-2Rβ, an...

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Detalles Bibliográficos
Autores principales: Kirschke, Sophia, Ogunsulire, Ireti, Selvakumar, Balachandar, Schumacher, Neele, Sezin, Tanya, Rose-John, Stefan, Scheffold, Alexander, Garbers, Christoph, Lokau, Juliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127578/
https://www.ncbi.nlm.nih.gov/pubmed/35398356
http://dx.doi.org/10.1016/j.jbc.2022.101910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127578/
https://www.ncbi.nlm.nih.gov/pubmed/35398356
http://dx.doi.org/10.1016/j.jbc.2022.101910

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