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Sex-specific lipid dysregulation in the Abca7 knockout mouse brain

Alzheimer’s disease is a devastating neurodegenerative disease that affects more women than men. The pathomechanism underlying the sex disparity, especially in the brain, is unclear. ABCA7 is one of the strongest susceptibility genes for Alzheimer’s disease. It mediates the transport of lipids acros...

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Detalles Bibliográficos
Autores principales: Fu, YuHong, He, Ying, Phan, Katherine, Pickford, Russell, Kim, Young-Bum, Dzamko, Nicolas, Halliday, Glenda M., Kim, Woojin Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127619/
https://www.ncbi.nlm.nih.gov/pubmed/35620166
http://dx.doi.org/10.1093/braincomms/fcac120