Highly enantioselective copper-catalyzed propargylic amination to access N-tethered 1,6-enynes

A highly enantioselective copper-catalyzed propargylic amination starting from benzylic allylic amines has been developed with a new chiral N,N,P ligand. A series of N-tethered 1,6-enynes were synthesized in good to excellent yields with excellent enantioselectivities. Utilization of transition meta...

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Detalles Bibliográficos
Autores principales: Li, Si-Jia, Huang, Jian, He, Jin-Yu, Zhang, Rui-Jin, Qian, Hao-Dong, Dai, Xue-Lin, Kong, Han-Han, Xu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127637/
https://www.ncbi.nlm.nih.gov/pubmed/35685332
http://dx.doi.org/10.1039/d0ra07698h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127637/
https://www.ncbi.nlm.nih.gov/pubmed/35685332
http://dx.doi.org/10.1039/d0ra07698h

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