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Affinity Chromatography‐Based Assays for the Screening of Potential Ligands Selective for G‐Quadruplex Structures

DNA G‐quadruplexes (G4s) are key structures for the development of targeted anticancer therapies. In this context, ligands selectively interacting with G4s can represent valuable anticancer drugs. Aiming at speeding up the identification of G4‐targeting synthetic or natural compounds, we developed a...

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Detalles Bibliográficos
Autores principales: Platella, Chiara, Napolitano, Ettore, Riccardi, Claudia, Musumeci, Domenica, Montesarchio, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127747/
https://www.ncbi.nlm.nih.gov/pubmed/35608081
http://dx.doi.org/10.1002/open.202200090