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Chemical Proteomics Reveals Off-Targets of the Anandamide Reuptake Inhibitor WOBE437

[Image: see text] Anandamide or N-arachidonoylethanolamine (AEA) is a signaling lipid that modulates neurotransmitter release via activation of the type 1 cannabinoid receptor (CB(1)R) in the brain. Termination of anandamide signaling is thought to be mediated via a facilitated cellular reuptake pro...

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Detalles Bibliográficos
Autores principales: Gagestein, Berend, Stevens, Anna F., Fazio, Domenico, Florea, Bogdan I., van der Wel, Tom, Bakker, Alexander T., Fezza, Filomena, Dulk, Hans den, Overkleeft, Herman S., Maccarrone, Mauro, van der Stelt, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127799/
https://www.ncbi.nlm.nih.gov/pubmed/35482948
http://dx.doi.org/10.1021/acschembio.2c00122