An eIF3d-dependent switch regulates HCMV replication by remodeling the infected cell translation landscape to mimic chronic ER stress

Regulated loading of eIF3-bound 40S ribosomes on capped mRNA is generally dependent upon the translation initiation factor eIF4E; however, mRNA translation often proceeds during physiological stress, such as virus infection, when eIF4E availability and activity are limiting. It remains poorly unders...

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Detalles Bibliográficos
Autores principales: Thompson, Letitia, Depledge, Daniel P., Burgess, Hannah M., Mohr, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127984/
https://www.ncbi.nlm.nih.gov/pubmed/35508137
http://dx.doi.org/10.1016/j.celrep.2022.110767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127984/
https://www.ncbi.nlm.nih.gov/pubmed/35508137
http://dx.doi.org/10.1016/j.celrep.2022.110767

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