Molecular Mechanisms of HIV Protease Inhibitors Against HPV-Associated Cervical Cancer: Restoration of TP53 Tumour Suppressor Activities

Cervical cancer is a Human Papilloma virus-related disease, which is on the rise in a number of countries, globally. Two essential oncogenes, E6 and E7, drive cell transformation and cancer development. These two oncoproteins target two of the most important tumour suppressors, p53 and pRB, for degr...

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Detalles Bibliográficos
Autores principales: Makgoo, Lilian, Mosebi, Salerwe, Mbita, Zukile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127998/
https://www.ncbi.nlm.nih.gov/pubmed/35620479
http://dx.doi.org/10.3389/fmolb.2022.875208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127998/
https://www.ncbi.nlm.nih.gov/pubmed/35620479
http://dx.doi.org/10.3389/fmolb.2022.875208

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