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Heterogeneity of Acetylcholine Receptor Autoantibody–Mediated Complement Activity in Patients With Myasthenia Gravis

BACKGROUND AND OBJECTIVES: Autoantibodies targeting the acetylcholine receptor (AChR), found in patients with myasthenia gravis (MG), mediate pathology through 3 mechanisms: complement-directed tissue damage, blocking of the acetylcholine binding site, and internalization of the AChR. Clinical assay...

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Detalles Bibliográficos
Autores principales: Obaid, Abeer H., Zografou, Chryssa, Vadysirisack, Douangsone D., Munro-Sheldon, Bailey, Fichtner, Miriam L., Roy, Bhaskar, Philbrick, William M., Bennett, Jeffrey L., Nowak, Richard J., O'Connor, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128035/
https://www.ncbi.nlm.nih.gov/pubmed/35473886
http://dx.doi.org/10.1212/NXI.0000000000001169