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Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer

Advanced pancreatic ductal adenocarcinoma (PDAC) is usually an incurable malignancy that needs newer therapeutic targets. Interleukin-1 receptor accessory protein (IL1RAP) is an innate immune mediator that regulates activation of pro-inflammatory and mitogenic signaling pathways. Immunohistochemistr...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Chen, Xiaoyi, Wang, Huamin, Gordon-Mitchell, Shanisha, Sahu, Srabani, Bhagat, Tushar D., Choudhary, Gaurav, Aluri, Srinivas, Pradhan, Kith, Sahu, Plabani, Carbajal, Milagros, Zhang, Hui, Agarwal, Beamon, Shastri, Aditi, Martell, Robert, Starczynowski, Daniel, Steidl, Ulrich, Maitra, Anirban, Verma, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128118/
https://www.ncbi.nlm.nih.gov/pubmed/35606824
http://dx.doi.org/10.1186/s13045-022-01286-4