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Elevated testicular apoptosis is associated with elevated sphingosine driven by gut microbiota in prediabetic sheep

BACKGROUND: Men with prediabetes often exhibit concomitant low-quality sperm production or even infertility, problems which urgently require improved therapeutic options. In this study, we have established a sheep model of diet-induced prediabetes that is associated with spermatogenic defects and ha...

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Detalles Bibliográficos
Autores principales: Sun, Yuanchao, Sun, Peng, Hu, Yanting, Shan, Liying, Geng, Qi, Gong, Yutian, Fan, Haitao, Zhang, Teng, Zhou, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128135/
https://www.ncbi.nlm.nih.gov/pubmed/35606800
http://dx.doi.org/10.1186/s12915-022-01326-y