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Intracranial pressure and optic disc changes in a rat model of obstructive hydrocephalus

BACKGROUND: The kaolin induced obstructive hydrocephalus (OHC) model is well known for its ability to increase intracranial pressure (ICP) in experimental animals. Papilledema (PE) which is a predominant hallmark of elevated ICP in the clinic has not yet been studied in this model using high-resolut...

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Detalles Bibliográficos
Autores principales: Hagen, Snorre Malm, Eftekhari, Sajedeh, Hamann, Steffen, Juhler, Marianne, Jensen, Rigmor H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128145/
https://www.ncbi.nlm.nih.gov/pubmed/35606718
http://dx.doi.org/10.1186/s12868-022-00716-w