Tumor endothelial cell‐induced CD8(+) T‐cell exhaustion via GPNMB in hepatocellular carcinoma

Tumor endothelial cells (TECs) promote tumor angiogenesis and regulate cytotoxic T cells in the tumor microenvironment. However, the roles of TECs for tumor‐infiltrating T‐cell in hepatocellular carcinoma (HCC) is still unknown. Here, we aimed to investigate how TECs influenced tumor growth and immu...

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Detalles Bibliográficos
Autores principales: Sakano, Yoshihiro, Noda, Takehiro, Kobayashi, Shogo, Sasaki, Kazuki, Iwagami, Yoshifumi, Yamada, Daisaku, Tomimaru, Yoshito, Akita, Hirofumi, Gotoh, Kunihito, Takahashi, Hidenori, Asaoka, Tadafumi, Tanemura, Masahiro, Wada, Hisashi, Doki, Yuichiro, Eguchi, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128167/
https://www.ncbi.nlm.nih.gov/pubmed/35289033
http://dx.doi.org/10.1111/cas.15331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128167/
https://www.ncbi.nlm.nih.gov/pubmed/35289033
http://dx.doi.org/10.1111/cas.15331

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