Cargando…

Tumor endothelial cell‐induced CD8(+) T‐cell exhaustion via GPNMB in hepatocellular carcinoma

Tumor endothelial cells (TECs) promote tumor angiogenesis and regulate cytotoxic T cells in the tumor microenvironment. However, the roles of TECs for tumor‐infiltrating T‐cell in hepatocellular carcinoma (HCC) is still unknown. Here, we aimed to investigate how TECs influenced tumor growth and immu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sakano, Yoshihiro, Noda, Takehiro, Kobayashi, Shogo, Sasaki, Kazuki, Iwagami, Yoshifumi, Yamada, Daisaku, Tomimaru, Yoshito, Akita, Hirofumi, Gotoh, Kunihito, Takahashi, Hidenori, Asaoka, Tadafumi, Tanemura, Masahiro, Wada, Hisashi, Doki, Yuichiro, Eguchi, Hidetoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128167/ https://www.ncbi.nlm.nih.gov/pubmed/35289033 http://dx.doi.org/10.1111/cas.15331

Ejemplares similares

Anti-tumor effect of avadomide in gemcitabine-resistant pancreatic ductal adenocarcinoma
por: Nishi, Hidemi, et al.
Publicado: (2023)

Prognostic value of functional SMAD4 localization in extrahepatic bile duct cancer
por: Takayama, Hirotoshi, et al.
Publicado: (2022)

Successful endovascular embolization of the common hepatic artery for pseudoaneurysm associated with pancreatic fistula after liver transplantation: a case report
por: Sasaki, Kazuki, et al.
Publicado: (2023)

A case report of Fontan procedure-related hepatocellular carcinoma: pure laparoscopic approach by low and stable pneumoperitoneum
por: Yokota, Yuki, et al.
Publicado: (2020)

Serum exosomal miR‐638 is a prognostic marker of HCC via downregulation of VE‐cadherin and ZO‐1 of endothelial cells
por: Yokota, Yuki, et al.
Publicado: (2021)

Difference between carbohydrate antigen 19‐9 and fluorine‐18 fluorodeoxyglucose positron emission tomography in evaluating the treatment efficacy of neoadjuvant treatment in patients with resectable and borderline resectable pancreatic ductal adenocarcinoma: Results of a dual‐center study
por: Akita, Hirofumi, et al.
Publicado: (2020)

The impact of cellular senescence and senescence‑associated secretory phenotype in cancer‑associated fibroblasts on the malignancy of pancreatic cancer
por: Higashiguchi, Masaya, et al.
Publicado: (2023)

A case of intraductal papillary neoplasm of the bile duct that developed 38 years after choledochoduodenostomy with invasive adenocarcinoma and lymph node metastasis
por: Kinoshita, Mitsuru, et al.
Publicado: (2019)

Endogenous CXCL9 affects prognosis by regulating tumor‐infiltrating natural killer cells in intrahepatic cholangiocarcinoma
por: Fukuda, Yasunari, et al.
Publicado: (2020)

Role of histone deacetylase 1 in distant metastasis of pancreatic ductal cancer
por: Shinke, Go, et al.
Publicado: (2018)

Pure laparoscopic liver resection for giant liver hemangioma with extrahepatic growth based on preoperative 3-dimensional simulation: A case report
por: Okumura, Yuichiro, et al.
Publicado: (2019)

MicroRNA‐181b‐5p, ETS1, and the c‐Met pathway exacerbate the prognosis of pancreatic ductal adenocarcinoma after radiation therapy
por: Tomihara, Hideo, et al.
Publicado: (2017)

Laparoscopy-assisted extended right hepatectomy for giant hemorrhagic hepatic cyst mimicking biliary cystadenocarcinoma: a case report
por: Fukuda, Yasunari, et al.
Publicado: (2019)

The blockade of interleukin‐33 released by hepatectomy would be a promising treatment option for cholangiocarcinoma
por: Nagaoka, Satoshi, et al.
Publicado: (2020)

MicroRNA-155 Controls Exosome Synthesis and Promotes Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma
por: Mikamori, Manabu, et al.
Publicado: (2017)

Preoperative neutrophil‐to‐lymphocyte ratio predicts healing time for postoperative pancreatic fistula after distal pancreatectomy
por: Toya, Keisuke, et al.
Publicado: (2021)

Partial hepatectomy for a patient with Rendu–Osler–Weber disease: a case report
por: Sekiguchi, Naoko, et al.
Publicado: (2023)

Short- and Long-term Outcomes of De Novo Liver Transplant Patients Treated With Once-Daily Prolonged-Release Tacrolimus
por: Okumura, Yuichiro, et al.
Publicado: (2017)

Clinicopathological significance of MYL9 expression in pancreatic ductal adenocarcinoma
por: Matsushita, Katsunori, et al.
Publicado: (2021)

Two cases of resectable pancreatic cancer diagnosed by open surgical biopsy after endoscopic ultrasound fine-needle aspiration failed to yield diagnosis: case reports
por: Toshiyama, Reishi, et al.
Publicado: (2017)

Agenesis of the left hepatic lobe undergoing laparoscopic hepatectomy for hepatocellular carcinoma: a case report
por: Matsushita, Katsunori, et al.
Publicado: (2017)

Magnetic compression anastomosis for the complete dehiscence of hepaticojejunostomy in a patient after living-donor liver transplantation
por: Kubo, Masahiko, et al.
Publicado: (2018)

A Histone Deacetylase Inhibitor Suppresses Epithelial-Mesenchymal Transition and Attenuates Chemoresistance in Biliary Tract Cancer
por: Sakamoto, Takuya, et al.
Publicado: (2016)

Different timing and risk factors of cause-specific pancreas graft loss after simultaneous pancreas kidney transplantation
por: Tomimaru, Yoshito, et al.
Publicado: (2022)

Middle segment pancreatectomy for a solid serous cystadenoma diagnosed by MRCP and review of the literature: A case report
por: Okumura, Yuichiro, et al.
Publicado: (2018)

Epithelial‐mesenchymal transition via transforming growth factor beta in pancreatic cancer is potentiated by the inflammatory glycoprotein leucine‐rich alpha‐2 glycoprotein
por: Otsuru, Toru, et al.
Publicado: (2019)

Characteristics of early‐onset pancreatic cancer and its association with familial pancreatic cancer and hereditary pancreatic cancer syndromes
por: Eguchi, Hidetoshi, et al.
Publicado: (2020)

A CD13 inhibitor, ubenimex, synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma
por: YAMASHITA, MASAFUMI, et al.
Publicado: (2016)

Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report
por: Mukai, Yosuke, et al.
Publicado: (2016)

Clinical Experience with Pancreas Graft Rescue From Severe Thrombus After Simultaneous Pancreas-Kidney Transplantation by Early Detection with Doppler Ultrasound: A Case Report
por: Takeda, Mitsunobu, et al.
Publicado: (2016)

A practical approach to pancreatic cancer immunotherapy using resected tumor lysate vaccines processed to express α-gal epitopes
por: Furukawa, Kenta, et al.
Publicado: (2017)

BRCA/Fanconi anemia pathway implicates chemoresistance to gemcitabine in biliary tract cancer
por: Nakashima, Shinsuke, et al.
Publicado: (2015)

Initial drainage‐related prognostic factors for perihilar cholangiocarcinoma: A single‐center retrospective study
por: Sato, Katsuhiko, et al.
Publicado: (2022)

Combined IFN-α and 5-FU treatment as a postoperative adjuvant following surgery for hepatocellular carcinoma with portal venous tumor thrombus
por: NAGANO, HIROAKI, et al.
Publicado: (2013)

A resected case of liver metastases from extra-adrenal retroperitoneal paraganglioma with von Recklinghausen’s disease 16 years after the initial surgery
por: Sakai, Kenji, et al.
Publicado: (2015)

Current state of pancreas transplantation in Japan based on the nationwide registry
por: Tomimaru, Yoshito, et al.
Publicado: (2021)

CD90- (Thy-1-) High Selection Enhances Reprogramming Capacity of Murine Adipose-Derived Mesenchymal Stem Cells
por: Kawamoto, Koichi, et al.
Publicado: (2013)

Randomized phase II study of gemcitabine and S-1 combination therapy versus gemcitabine and nanoparticle albumin-bound paclitaxel combination therapy as neoadjuvant chemotherapy for resectable/borderline resectable pancreatic ductal adenocarcinoma (PDAC-GS/GA-rP2, CSGO-HBP-015)
por: Yamada, Daisaku, et al.
Publicado: (2021)

Liver resection combined with inferior vena cava resection and reconstruction using artificial vascular graft: A literature review
por: Tomimaru, Yoshito, et al.
Publicado: (2018)

Identification of Novel and Noninvasive Biomarkers of Acute Cellular Rejection After Liver Transplantation by Protein Microarray
por: Okubo, Keita, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_mp97f194v6ms4fndgklc3qelf4