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Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region
BACKGROUND: Genome-wide association studies of asthma have revealed robust associations with variation across the human leukocyte antigen (HLA) complex with independent associations in the HLA class I and class II regions for both childhood-onset asthma (COA) and adult-onset asthma (AOA). However, t...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128203/ https://www.ncbi.nlm.nih.gov/pubmed/35606880 http://dx.doi.org/10.1186/s13073-022-01058-2 |