Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region

BACKGROUND: Genome-wide association studies of asthma have revealed robust associations with variation across the human leukocyte antigen (HLA) complex with independent associations in the HLA class I and class II regions for both childhood-onset asthma (COA) and adult-onset asthma (AOA). However, t...

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Detalles Bibliográficos
Autores principales: Clay, Selene M., Schoettler, Nathan, Goldstein, Andrew M., Carbonetto, Peter, Dapas, Matthew, Altman, Matthew C., Rosasco, Mario G., Gern, James E., Jackson, Daniel J., Im, Hae Kyung, Stephens, Matthew, Nicolae, Dan L., Ober, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128203/
https://www.ncbi.nlm.nih.gov/pubmed/35606880
http://dx.doi.org/10.1186/s13073-022-01058-2

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