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Comprehensive assessment of differential ChIP-seq tools guides optimal algorithm selection

BACKGROUND: The analysis of chromatin binding patterns of proteins in different biological states is a main application of chromatin immunoprecipitation followed by sequencing (ChIP-seq). A large number of algorithms and computational tools for quantitative comparison of ChIP-seq datasets exist, but...

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Detalles Bibliográficos
Autores principales: Eder, Thomas, Grebien, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128273/
https://www.ncbi.nlm.nih.gov/pubmed/35606795
http://dx.doi.org/10.1186/s13059-022-02686-y