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Comprehensive assessment of differential ChIP-seq tools guides optimal algorithm selection
BACKGROUND: The analysis of chromatin binding patterns of proteins in different biological states is a main application of chromatin immunoprecipitation followed by sequencing (ChIP-seq). A large number of algorithms and computational tools for quantitative comparison of ChIP-seq datasets exist, but...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128273/ https://www.ncbi.nlm.nih.gov/pubmed/35606795 http://dx.doi.org/10.1186/s13059-022-02686-y |