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BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation

BACKGROUND: X chromosome inactivation (XCI) is an epigenetic phenomenon that one of two X chromosomes in females is transcriptionally silenced during early embryonic development. Skewed XCI has been reported to be associated with some X-linked diseases. There have been several methods measuring the...

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Detalles Bibliográficos
Autores principales: Yu, Wen-Yi, Zhang, Yu, Li, Meng-Kai, Yang, Zi-Ying, Fung, Wing Kam, Zhao, Pei-Zhen, Zhou, Ji-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128296/
https://www.ncbi.nlm.nih.gov/pubmed/35610583
http://dx.doi.org/10.1186/s12859-022-04721-y