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Clinical Significance of a CD3/CD8-Based Immunoscore in Neuroblastoma Patients Using Digital Pathology

BACKGROUND: Infiltrating immune cells have been reported as prognostic markers in many cancer types. We aimed to evaluate the prognostic role of tumor-infiltrating lymphocytes, namely CD3+ T cells, CD8+ cytotoxic T cells and memory T cells (CD45RO+), in neuroblastoma. PATIENTS AND METHODS: Immunohis...

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Detalles Bibliográficos
Autores principales: Zeng, Liang, Li, Shu-Hua, Xu, Shuo-Yu, Chen, Kai, Qin, Liang-Jun, Liu, Xiao-Yun, Wang, Fang, Fu, Sha, Deng, Ling, Wang, Feng-Hua, Miao, Lei, Li, Le, Liu, Na, Wang, Ran, Wang, Hai-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128405/
https://www.ncbi.nlm.nih.gov/pubmed/35619699
http://dx.doi.org/10.3389/fimmu.2022.878457