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Topical Simvastatin Improves Lesions of Diffuse Normolipemic Plane Xanthoma by Inhibiting Foam Cell Pyroptosis

Xanthoma pathogenesis is speculated to be associated with oxidized low-density lipoprotein (ox-LDL) deposition, although this remains unclear. Most patients with diffuse plane xanthomas present elevated blood lipid levels, and they benefit from treatment with oral lipid-lowering agents. However, the...

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Detalles Bibliográficos
Autores principales: Zha, Siyuan, Yu, Xia, Wang, Xiaoxiao, Gu, Yan, Tan, Yidong, Lu, Ying, Yao, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128406/
https://www.ncbi.nlm.nih.gov/pubmed/35619689
http://dx.doi.org/10.3389/fimmu.2022.865704