PD-L1 Inhibits T Cell-Induced Cytokines and Hyaluronan Expression via the CD40-CD40L Pathway in Orbital Fibroblasts From Patients With Thyroid Associated Ophthalmopathy

Thyroid associated ophthalmopathy (TAO), characterized by T cell infiltration and orbital fibroblast activation, is an organ-specific autoimmune disease which is still short of effective and safety therapeutic drugs. The PD-1/PD-L1 pathway has been reported hindering the progression of Graves’ disea...

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Detalles Bibliográficos
Autores principales: Liu, Zhibin, Liu, Yao, Liu, Mingming, Gong, Qingjia, Shi, Anjie, Li, Xiuhong, Bai, Xu, Guan, Xiaoyue, Hao, Bing, Liu, Feila, Zhou, Xing, Yuan, Hongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128409/
https://www.ncbi.nlm.nih.gov/pubmed/35619700
http://dx.doi.org/10.3389/fimmu.2022.849480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128409/
https://www.ncbi.nlm.nih.gov/pubmed/35619700
http://dx.doi.org/10.3389/fimmu.2022.849480

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