Disruption of the Cytoplasmic Membrane Structure and Barrier Function Underlies the Potent Antiseptic Activity of Octenidine in Gram-Positive Bacteria

The antimicrobial killing mechanism of octenidine (OCT), a well-known antiseptic is poorly understood. We recently reported its interaction with Gram-negative bacteria by insertion of OCT into the outer and cytoplasmic membrane of Escherichia coli, resulting in a chaotic lipid rearrangement and rapi...

Descripción completa

Detalles Bibliográficos
Autores principales: Malanovic, Nermina, Buttress, Jessica A., Vejzovic, Djenana, Ön, Ayse, Piller, Paulina, Kolb, Dagmar, Lohner, Karl, Strahl, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128513/
https://www.ncbi.nlm.nih.gov/pubmed/35481757
http://dx.doi.org/10.1128/aem.00180-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128513/
https://www.ncbi.nlm.nih.gov/pubmed/35481757
http://dx.doi.org/10.1128/aem.00180-22

Ejemplares similares