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Disruption of the Cytoplasmic Membrane Structure and Barrier Function Underlies the Potent Antiseptic Activity of Octenidine in Gram-Positive Bacteria

The antimicrobial killing mechanism of octenidine (OCT), a well-known antiseptic is poorly understood. We recently reported its interaction with Gram-negative bacteria by insertion of OCT into the outer and cytoplasmic membrane of Escherichia coli, resulting in a chaotic lipid rearrangement and rapi...

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Detalles Bibliográficos
Autores principales:	Malanovic, Nermina, Buttress, Jessica A., Vejzovic, Djenana, Ön, Ayse, Piller, Paulina, Kolb, Dagmar, Lohner, Karl, Strahl, Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128513/ https://www.ncbi.nlm.nih.gov/pubmed/35481757 http://dx.doi.org/10.1128/aem.00180-22

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