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Chimeric oligonucleotides combining guide RNA and single-stranded DNA repair template effectively induce precision gene editing

The ability to precisely alter the genome holds immense potential for molecular biology, medicine and biotechnology. The development of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) into a genomic editing tool has vastly simplified genome engineering. Here, we explored the u...

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Detalles Bibliográficos
Autores principales: Ghosh, Avantika, Myacheva, Ksenia, Riester, Marisa, Schmidt, Carla, Diederichs, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128553/
https://www.ncbi.nlm.nih.gov/pubmed/35465826
http://dx.doi.org/10.1080/15476286.2022.2067713