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Chimeric oligonucleotides combining guide RNA and single-stranded DNA repair template effectively induce precision gene editing
The ability to precisely alter the genome holds immense potential for molecular biology, medicine and biotechnology. The development of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) into a genomic editing tool has vastly simplified genome engineering. Here, we explored the u...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128553/ https://www.ncbi.nlm.nih.gov/pubmed/35465826 http://dx.doi.org/10.1080/15476286.2022.2067713 |