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Investigating Flubendazole as an Anthelmintic Treatment for Guinea Worm (Dracunculus medinensis): Clinical Trials in Laboratory-Reared Ferrets and Domestic Dogs in Chad

Dracunculus medinensis (Guinea worm [GW]), a zoonotic nematode targeted for eradication, has been managed using interventions aimed at humans; however, increases in domestic dog GW infections highlight the need for novel approaches. We conducted two clinical trials evaluating the efficacy of subcuta...

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Detalles Bibliográficos
Autores principales: Cleveland, Christopher A., Garrett, Kayla B., Box, Erin K., Thompson, Alec T., Haynes, Ellen K., Elder, Deborah L., Richards, Robert L., Majewska, Ania A., Guagliardo, Sarah Anne J., Wiegand, Ryan E., Bryan II, John A., Torres-Velez, Fernando, Unterwegner, Karmen, Romero, Mario, Zirimwabagabo, Hubert, Sidouin, Metinou, Oaukou, Philip Tchindebet, Ada, Mbang Mahammat, Ngandolo, Bongo Nare Richard, Mackenzie, Charles D., Geary, Timothy G., Weiss, Adam J., Yabsley, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128682/
https://www.ncbi.nlm.nih.gov/pubmed/35226875
http://dx.doi.org/10.4269/ajtmh.21-1222