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CGRP and the Calcitonin Receptor are Co-Expressed in Mouse, Rat and Human Trigeminal Ganglia Neurons

The neuropeptide calcitonin gene-related peptide (CGRP) is expressed in the trigeminal ganglia, a key site in craniofacial pain and migraine. CGRP potently activates two receptors: the CGRP receptor and the AMY(1) receptor. These receptors are heterodimers consisting of receptor activity-modifying p...

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Detalles Bibliográficos
Autores principales: Rees, Tayla A., Russo, Andrew F., O’Carroll, Simon J., Hay, Debbie L., Walker, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128745/
https://www.ncbi.nlm.nih.gov/pubmed/35620595
http://dx.doi.org/10.3389/fphys.2022.860037