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Half-Sandwich Arene Ruthenium(II) Thiosemicarbazone Complexes: Evaluation of Anticancer Effect on Primary and Metastatic Ovarian Cancer Cell Lines

In this study, we describe the synthesis, characterization and antiproliferative activity of three organo-ruthenium(II) half-sandwich complexes [RuCl(η(6)-p-cym)(N,S-L)]Cl (I, II, and III). To form these complexes, three thiosemicarbazone ligands (TSCs) were synthesized; L = 5-nitro-2-carboxyaldehyd...

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Detalles Bibliográficos
Autores principales: Guler, Seminay, Kayali, Hulya Ayar, Sadan, Egemen Orkun, Sen, Betul, Subasi, Elif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128756/
https://www.ncbi.nlm.nih.gov/pubmed/35620291
http://dx.doi.org/10.3389/fphar.2022.882756