Prion-like α-synuclein pathology in the brain of infants with Krabbe disease

Krabbe disease is an infantile neurodegenerative disorder resulting from pathogenic variants in the GALC gene that causes accumulation of the toxic sphingolipid psychosine. GALC variants are also associated with Lewy body diseases, an umbrella term for age-associated neurodegenerative diseases in wh...

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Detalles Bibliográficos
Autores principales: Hatton, Christopher, Ghanem, Simona S., Koss, David J., Abdi, Ilham Y., Gibbons, Elizabeth, Guerreiro, Rita, Bras, Jose, Walker, Lauren, Gelpi, Ellen, Heywood, Wendy, Outeiro, Tiago F., Attems, Johannes, McFarland, Robert, Forsyth, Rob, El-Agnaf, Omar M., Erskine, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128812/
https://www.ncbi.nlm.nih.gov/pubmed/34999780
http://dx.doi.org/10.1093/brain/awac002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128812/
https://www.ncbi.nlm.nih.gov/pubmed/34999780
http://dx.doi.org/10.1093/brain/awac002

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