Intra-patient Heterogeneity of BRAF and NRAS Molecular Alterations in Primary Melanoma and Metastases

Mutations in MAPK signalling genes are driver events in melanoma, and have therapeutic relevance in the metastatic and adjuvant setting. This study evaluated the intra-patient heterogeneity of BRAF, NRAS and c-KIT mutational status between 30 primary melanomas and 39 related metastases, using molecu...

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Detalles Bibliográficos
Autores principales: PELLEGRINI, Cristina, CARDELLI, Ludovica, DE PADOVA, Marina, DI NARDO, Lucia, CICIARELL, Valeria, ROCCO, Tea, CIPOLLONI, Gianluca, CLEMENTI, Marco, CORTELLINI, Alessio, VENTURA, Alessandra, LEOCATA, Pietro, FARGNOLI, Maria Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Publication of Acta Dermato-Venereologica 2020
Materias:
Investigative Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128895/
https://www.ncbi.nlm.nih.gov/pubmed/31774543
http://dx.doi.org/10.2340/00015555-3382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128895/
https://www.ncbi.nlm.nih.gov/pubmed/31774543
http://dx.doi.org/10.2340/00015555-3382

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